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September, 25th


8:30 – 9:00 h -  Registration


9:00 – 9:30 h – Welcome and Introduction to the “IT-Liver” ITN Marie Curie Action.  

Isabel Fabregat (Bellvitge Biomedical Research Institute, IDIBELL, Barcelona, Spain)


Sesion I. Genomics and epigenomics.

Chairs: Wolfgang Mikulits (Medical University of Vienna, Austria) and Isabel Fabregat (IDIBELL, Barcelona, Spain)


9:30-10:15 h

“Next-generation-sequencing based genomics, transcriptomics and epigenetics in cancer research: technologies, applications and data management”

Peter Winter, GenXPro, GmbH, Frankfurt, Germany.


 10:15-11:00 h

“Uncovering and understanding splicing through massively parallel sequencing” Roderic Guigó, Centre for Genomic Regulation (CRG), Barcelona, Spain.


11:00-11:30 h Coffee


11:30-12:15 h

“Molecular classification and drivers as target for therapies in hepatocellular carcinoma (HCC)”

Josep Llovet, Mount Sinai Liver Cancer Research Programme, New York, USA, and CIBERehd, Hospital Clínic, Barcelona, Spain.


12:15-13:00 h

“Epigenetics and Epigenomics in Cancer”

Manel Esteller. Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.


13:00 – 13:45 h

"The reversibility of the epithelial-mesenchymal transition (EMT) in development and cancer progression”.

M. Ángela Nieto. Instituto de Neurociencias CSIC-UMH, San Juan de Alicante, Spain.


14:00 – 15:00 h Lunch


Sesion II. Proteomics and metabolomics

Chair: Stefano Leporatti (CNR-Nano, Lecce, Italy)


15:30-16:15 h

"Biomedical applications of Protein-Protein interaction networks"

Baldo Oliva, Departament de Ciencies Experimentals i de la Salut. Universitat Pompeu Fabra. Spain.

Angels Sierra, Institut d'Investigacions Biomèdiques August Pi i Sunyer- IDIBAPS, Barcelona, Spain


16:15-17:00 h

“Understanding and targeting metabolism for drug discovery in multifactorial diseases "

Marta Cascante. Faculty of Biology and Institute of Biomedicine of University of Barcelona (IBUB), Barcelona, Spain.


17:00-17:45 h

 “OMICs in Nonalcoholic Fatty Liver disease (NAFLD)”

 María L Martínez-Chantar. CIC-bioGUNE and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Technology Park of Bizkaia, Bizkaia, Spain.


September, 26th


Sesion III. Cytomics and image analyses

Chair: Aránzazu Sánchez, Complutense University, Madrid, Spain


9:00-9:45 h

“Cytomics in the XXI century”,

Enrique O'Connor Facultad de Medicina, Universidad de Valencia, Spain.


9:30-10:30 h

 “High content image analysis in high throughput screens”.

Martin Stöter, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.


10:30 – 11:00  Coffee

Sesion IV. Thematic session: TGF-β in human pathologies

Chairs: Gianluigi Giannelli (University of Bari, Italy) and Michael Lahn (Lilly Deutschland GmbH, Bad Homberg, Germany)


11:00-11:45 h

“Marfan syndrome: from gene to therapy”.

Bart Loeys. University of Antwerp and Antwerp University Hospital, Antwerp, Belgium.


11:45-12:30 h

“Stromal TGF beta signals in Colon Cancer Metastasis”.

Elena Sancho. Institut for Research in Biomedicine (IRB), Barcelona, Spain.


12:30-13:15 h

TGF-&beta gene signatures in liver primary tumors.

Cédric Coulouarn. Inserm U991. Hôpital Pontchaillou, Rennes cedex, France.


13:30 – 15:00 Lunch


15:00- 15:45 h

“The TGF-b pathway as a therapeutic target”.

Joan Seoane. Vall d'Hebron Research Institute, Barcelona, Spain.


15:45- 16:00 h

“TGF-beta signaling in breast cancer: identification of new drug targets”

Peter ten_Dijke. Leiden University Medical Center (LUMC), Leiden, The Netherlands.

16:00- 16:30 Concluding remarks

Contact information

Isabel Fabregat (IDIBELL, Barcelona)